Investigating the shared genetic architecture between primary sclerosing cholangitis and inflammatory bowel diseases: a Mendelian randomization study

Abstract Background Several studies have found that primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) are closely associated. However, the direction and causality of their interactions remain unclear. Thus, this study employs Mendelian Randomization to explore whether there a...

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Bibliographic Details

Published in:	BMC Gastroenterology
Main Authors:	Xuan Dong, Li-Li Gong, Mei-Zhu Hong, Jin-Shui Pan
Format:	Article
Language:	English
Published:	BMC 2024-02-01
Subjects:	Mendelian randomization Primary sclerosing cholangitis Ulcerative colitis Crohn’s disease
Online Access:	https://doi.org/10.1186/s12876-024-03162-6