Targeting IL13Rα2 in melanoma with a bispecific T-cell engager: expression profiling and preclinical evaluation

Background Melanoma is a highly aggressive skin cancer, especially in advanced stages. While current treatments such as targeted therapies and immunotherapies have made significant progress, challenges like drug resistance and limited effectiveness in some patients persist. Therefore, ongoing develo...

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Bibliographic Details
Published in:Journal for ImmunoTherapy of Cancer
Main Authors: David B Weiner, Meenhard Herlyn, Pratik S Bhojnagarwala, Daniel H Park, Shushu Zhao, Yeqing Chen, Cory Livingston, Joshua Jose, Yangcheng Gao
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Online Access:https://jitc.bmj.com/content/13/6/e011073.full