A phase 2, double-blind, placebo-controlled trial of a valproate/lithium combination in ALS patients

Background: Few treatments are currently available for amyotrophic lateral sclerosis (ALS). A combination of lithium carbonate and valproic acid (VPA-Li) was shown to inhibit motor neuron death and delay disease progression. Methods: Outpatients with a typical ALS presentation were enrolled in a ran...

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發表在:	Neurología
Main Authors:	M.-C. Boll, M. Alcaraz-Zubeldia, C. Rios, D. González-Esquivel, S. Montes
格式:	Article
語言:	西班牙语
出版:	Elsevier España 2025-01-01
主題:	Esclerosis lateral amiotrófica Ensayo clínico Doble ciego Tratamiento sinérgico Neuroprotección
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S0213485322000779