Effect of chronic administration of ostruthin on depression-like behavior in chronically stressed mice

We have previously shown that a single dose of a TREK-1 channel activator, ostruthin, exhibited antidepressant and anxiolytic effects in acute behavioral test models in mice. To assess the potential clinical application, it is essential to evaluate the effects of long-term administration of ostruthi...

Full description

Bibliographic Details

Published in:	IBRO Neuroscience Reports
Main Authors:	Masayoshi Okada, Thi Thu Thuy Tran
Format:	Article
Language:	English
Published:	Elsevier 2024-06-01
Subjects:	Ostruthin Antidepressant Chronic unpredictable mild stress TREK-1 channel And drug-metabolizing enzyme
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667242124000526