Case report: Optical genome mapping revealed double rearrangements in a male undergoing preimplantation genetic testing

Chromosome rearrangement is one of the main causes of abortion. In individuals with double chromosomal rearrangements, the abortion rate and the risk of producing abnormal chromosomal embryos are increased. In our study, preimplantation genetic testing for structural rearrangement (PGT-SR) was perfo...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Jun Ren, Yuezhi Keqie, Yutong Li, Lingping Li, Min Luo, Meng Gao, Cuiting Peng, Han Chen, Ting Hu, Xinlian Chen, Shanling Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	optical genome mapping PGT-SR complex chromosome rearrangements cryptic reciprocal translocation FISH
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2023.1132404/full