A UPLC-ESI-MS/MS Method for Simultaneous Quantitation of Chlorogenic Acid, Scutellarin, and Scutellarein in Rat Plasma: Application to a Comparative Pharmacokinetic Study in Sham-Operated and MCAO Rats after Oral Administration of Erigeron breviscapus Extract

Erigeron breviscapus, a traditional Chinese medicine, is clinically used for the treatment of occlusive cerebral vascular diseases. We developed a sensitive and reliable ultra-performance liquid chromatography-electrospray-tandem mass spectrometry (UPLC-ESI-MS/MS) method for simultaneous quantitatio...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Siying Chen, Mei Li, Yueting Li, Hejia Hu, Ying Li, Yong Huang, Lin Zheng, Yuan Lu, Jie Hu, Yanyu Lan, Aimin Wang, Yongjun Li, Zipeng Gong, Yonglin Wang
Format:	Article
Language:	English
Published:	MDPI AG 2018-07-01
Subjects:	Erigeron breviscapus extract UPLC-ESI-MS/MS cerebral ischemia reperfusion injury scutellarin scutellarein
Online Access:	http://www.mdpi.com/1420-3049/23/7/1808