Columbianadin Dampens In Vitro Inflammatory Actions and Inhibits Liver Injury via Inhibition of NF-κB/MAPKs: Impacts on ^∙OH Radicals and HO-1 Expression

Columbianadin (CBN), a natural coumarin isolated from <i>Angelica decursiva,</i> is reported to have numerous biological activities, including anticancer and platelet aggregation inhibiting properties. Here, we investigated CBN’s anti-inflammatory effect in lipopolysaccharide (LPS)-stimu...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Thanasekaran Jayakumar, Shaw-Min Hou, Chao-Chien Chang, Tsorng-Harn Fong, Chih-Wei Hsia, Yen-Jen Chen, Wei-Chieh Huang, Periyakali Saravanabhavan, Manjunath Manubolu, Joen-Rong Sheu, Chih-Hsuan Hsia
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Subjects:	columbianadin LPS hydroxyl radicals HO-1 expression liver-injury NF-κB/MAPK signaling pathways
Online Access:	https://www.mdpi.com/2076-3921/10/4/553