Detection of I491F and V170F rpoB mutations associated with misdiagnosis of rifampicin resistance among patients with drug-susceptible tuberculosis treatment failure, Myanmar, 2022

Objective: Detecting rifampicin (RIF) resistance is crucial in selecting tuberculosis (TB) treatment. Recently, several studies reported that I491F and V170F rpoB mutations were found with a varying prevalence. This study aimed to find out RIF resistance missed by routine diagnostic assays using nex...

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Bibliographic Details

Published in:	Journal of Global Antimicrobial Resistance
Main Authors:	Phyu Win Ei, Mi Mi Htwe, Myat Htut Nyunt, Aye Su Mon, Zaw Myint, Wint Wint Nyunt, Su Mon Win, Sandar Aung, Wai Myat Thwe, Wah Wah Aung
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Subjects:	Rifampicin resistant TB rpoB mutation I491F V170F Treatment failure Myanmar
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213716525000013