The expression of glucocorticoid and mineralocorticoid receptors in pituitary tumors causing Cushing’s disease and silent corticotroph tumors

ObjectivePituitary neuroendocrine corticotroph tumors commonly cause Cushing’s disease (CD) that results from increased adrenocorticotropic hormone (ACTH) secretion by the pituitary tumor and consequent increase of cortisol levels in blood. However, in some patients, corticotroph tumors remain clini...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Paulina Kober, Natalia Rusetska, Beata J. Mossakowska, Maria Maksymowicz, Monika Pękul, Grzegorz Zieliński, Andrzej Styk, Jacek Kunicki, Łukasz Działach, Przemysław Witek, Mateusz Bujko
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	pituitary neuroendocrine tumor (PitNET) Cushing’s disease (CD) silent corticotroph adenoma NR3C1 NR3C2 hypothalamic - pituitary - adrenal axis
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1124646/full