Comparative analyses define differences between BHD-associated renal tumour and sporadic chromophobe renal cell carcinomaResearch in context

Summary: Background: Birt-Hogg-Dubé (BHD) syndrome, caused by germline alteration of folliculin (FLCN) gene, develops hybrid oncocytic/chromophobe tumour (HOCT) and chromophobe renal cell carcinoma (ChRCC), whereas sporadic ChRCC does not harbor FLCN alteration. To date, molecular characteristics o...

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Published in:	EBioMedicine
Main Authors:	Ryosuke Jikuya, Todd A. Johnson, Kazuhiro Maejima, Jisong An, Young-Seok Ju, Hwajin Lee, Kyungsik Ha, WooJeung Song, Youngwook Kim, Yuki Okawa, Shota Sasagawa, Yuki Kanazashi, Masashi Fujita, Seiya Imoto, Taku Mitome, Shinji Ohtake, Go Noguchi, Sachi Kawaura, Yasuhiro Iribe, Kota Aomori, Tomoyuki Tatenuma, Mitsuru Komeya, Hiroki Ito, Yusuke Ito, Kentaro Muraoka, Mitsuko Furuya, Ikuma Kato, Satoshi Fujii, Haruka Hamanoue, Tomohiko Tamura, Masaya Baba, Toshio Suda, Tatsuhiko Kodama, Kazuhide Makiyama, Masahiro Yao, Brian M. Shuch, Christopher J. Ricketts, Laura S. Schmidt, W. Marston Linehan, Hidewaki Nakagawa, Hisashi Hasumi
Format:	Article
Language:	English
Published:	Elsevier 2023-06-01
Subjects:	Birt-Hogg-Dubé (BHD) syndrome Chromophobe renal cell carcinoma (ChRCC) Folliculin (FLCN) Renal tumour predisposition syndrome
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396423001615