Galectin-9 expression defines exhausted T cells and impaired cytotoxic NK cells in patients with virus-associated solid tumors

Background We have previously reported that the upregulation of galectin-9 (Gal-9) on CD4+ and CD8+ T cells in HIV patients was associated with impaired T cell effector functions. Gal-9 is a ligand for T cell immunoglobulin and mucin domain-3, and its expression on T cells in cancer has not been inv...

詳細記述

書誌詳細
出版年:Journal for ImmunoTherapy of Cancer
主要な著者: John W Walker, Isobel Okoye, Lai Xu, Melika Motamedi, Pallavi Parashar, Shokrollah Elahi
フォーマット: 論文
言語:英語
出版事項: BMJ Publishing Group 2020-10-01
オンライン・アクセス:https://jitc.bmj.com/content/8/2/e001849.full