Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus

BackgroundMitochondrial dysfunction is implicated in the pathogenesis of systemic lupus erythematosus (SLE). Single-cell mitochondrial mass (SCMM), low mitochondrial membrane potential (MMP-Low) in lymphocytes, and circulating mitochondrial DNA (mtDNA) can reflect mitochondrial impairment and may se...

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Bibliographic Details

Published in:	Frontiers in Molecular Biosciences
Main Authors:	Guanfei Zhao, Haolong Li, Yutong Miao, Linlin Cheng, Yuying Chen, Yuan Huang, Hongyun Zhao, Yongmei Liu, Yipei Jing, Shasha Wang, Yongzhe Li, Rui Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	systemic lupus erythematosus mitochondrial mass mitochondrial membrane potential mitochondrial DNA lymphocytes
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2025.1585847/full