Integration of metabolomics and transcriptomics identifies pathways involved in intermittent fasting and renal injury induced by a high-fat diet in mice

Obesity, a worldwide epidemic, is often accompanied by renal dysfunction or accelerating kidney disease. Intermittent fasting (IF) has become a popular weight loss approach, but the data for obesity-related kidney disease are very limited. Moreover, there is currently no combined omics study on its...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Lingfeng Yuan, Xiaobo Song, Yisheng Luan, Weihao Hong, Yue Hu, Shuqiao Ding, Bing Zhang, Yingzhe Xiong
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	obesity intermittent fasting renal injury metabolomics transcriptomics
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2025.1683573/full