The influence of nutritional status, lipid profile, leptin concentration and polymorphism of genes encoding leptin and neuropeptide Y on the effectiveness of immunotherapy in advanced NSCLC patients

Abstract Introduction Neuropeptide Y is a neurotransmitter in the nervous system and belongs to the orexigenic system that increases appetite. Its excessive secretion leads to obesity. Leptin is a pro-inflammatory adipokine (produced in adipose tissue) induced in obesity and may mediate increased an...

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Bibliographic Details

Published in:	BMC Cancer
Main Authors:	Małgorzata Frąk, Anna Grenda, Paweł Krawczyk, Barbara Kuźnar-Kamińska, Paweł Pazdrowski, Karolina Kędra, Izabela Chmielewska, Janusz Milanowski
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	Non-small cell lung cancer Immunotherapy Obesity Lipid profile Leptin
Online Access:	https://doi.org/10.1186/s12885-024-12716-6