Development of the optimal scheme for the synthesis of the dipeptide TSPO ligand, N-phenylpropionyl-L-tryptophanyl-L-leucine amide (GD-102), a potential anxiolytic drug

Previously at the Zakusov Research Institute of Pharmacology the first dipeptide ligand TSPO, the compound N-phenylpropionyl-L-tryptophanyl-L-leucine amide (laboratory code GD-102), was designed and synthesized. The anxiolytic activity was detected for this compound at the doses 0.01–1.0 mg/kg intra...

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Bibliographic Details

Published in:	Фармакокинетика и Фармакодинамика
Main Author:	O. A. Deeva
Format:	Article
Language:	Russian
Published:	LLC “Publisher OKI” 2024-01-01
Subjects:	dipeptide gd-102 tspo ligand peptide synthesis
Online Access:	https://www.pharmacokinetica.ru/jour/article/view/396