Cathepsin X is secreted by human osteoblasts, digests CXCL-12 and impairs adhesion of hematopoietic stem and progenitor cells to osteoblasts

Background Hematopoietic stem cells are retained within discrete bone marrow niches through the effects of cell adhesion molecules and chemokine gradients. However, a small proportion of hematopoietic stem cells can also be found trafficking in the peripheral blood. During induced stem cell mobiliza...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Haematologica
المؤلفون الرئيسيون: Nicole D. Staudt, Wilhelm K. Aicher, Hubert Kalbacher, Stefan Stevanovic, Adriana K. Carmona, Matthew Bogyo, Gerd Klein
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Ferrata Storti Foundation 2010-09-01
الوصول للمادة أونلاين:https://haematologica.org/article/view/5707