A proteasome-dependent inhibition of SIRT-1 by the resveratrol analogue 4,4′-dihydroxy-trans-stilbene

Background and aim: Resveratrol (RSV), is a stilbene-based compound exerting wide biological properties. Its analogue 4,4′-dihydroxy-trans-stilbene (DHS) has shown improved bioavailability and antiproliferative activity in vitro and in vivo. One of the hypotheses on how resveratrol works is based on...

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Bibliographic Details

Published in:	Journal of Traditional and Complementary Medicine
Main Authors:	Vittoria Livraghi, Laura Mazza, Federica Chiappori, Miriana Cardano, Ornella Cazzalini, Roberto Puglisi, Rossana Capoferri, Anna Pozzi, Lucia Anna Stivala, Laura Zannini, Monica Savio
Format:	Article
Language:	English
Published:	Elsevier 2024-09-01
Subjects:	4,4′-dihydroxystilbene Sirtuin-1 Resveratrol Deacetylation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2225411024000208