Dasatinib and Quercetin alleviate type 2 diabetic osteoporosis by regulating serum metabolite and gut microbiome

Type 2 diabetic osteoporosis (T2DOP) is a complex metabolic bone disorder characterized by reduced bone density and increased risk of osteoporosis in patients with type 2 diabetes mellitus. The etiology of T2DOP is multifactorial, involving hyperglycemia, insulin resistance, and gut microbiota dysbi...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Junzheng Yang, Hua Zhang, Zhuoxu Gu, Guanghui Zhou, Guihong Liang, Lingfeng Zeng, Jinlong Zhao, Weiyi Yang, Jun Liu, Jianke Pan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	senolytics bone metabolic diseases gut microbiota metabolomics type 2 diabete mellitus
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1631082/full