The olfactory receptor OR51E2 regulates prostate cancer aggressiveness and modulates STAT3 in prostate cancer cells and in xenograft tumors

Abstract Background Despite advancements in the detection and treatment of prostate cancer, the molecular mechanisms underlying its progression remain unclear. This study aimed to investigate the role of the receptor OR51E2, which is commonly upregulated in prostate cancer, in the progression of thi...

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Bibliographic Details

Published in:	BMC Cancer
Main Authors:	Mikkel Thy Thomsen, Morten Busk, Dalin Zhang, Chun-Lung Chiu, Hongjuan Zhao, Fernando Jose Garcia-Marques, Abel Bermudez, Sharon Pitteri, Michael Borre, James D. Brooks, Jens Randel Nyengaard
Format:	Article
Language:	English
Published:	BMC 2025-03-01
Subjects:	Prostate cancer progression Cancer physiology Transcriptomics Proteomics Cell signaling GPCR
Online Access:	https://doi.org/10.1186/s12885-025-13928-0