Sphingosine 1-phosphate receptor 1 modulators exert neuroprotective effects in central nervous system disorders

The sphingosine 1-phosphate (S1P) signaling pathway has important and diverse functions. S1P receptors (S1PRs) are involved in the regulation of lymphocyte trafficking, cardio-cerebral function, vascular permeability, and bronchiolar tone, and have been recognized as therapeutic targets for a variet...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Shouming Chen, Lan Wu, Bingchen Lang, Guoyan Zhao, Wensheng Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Subjects:	S1P S1PR CNS MS NDDs brain injury
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1516991/full