Synthesis and Pharmacological Characterization of New Photocaged Agonists for Histamine H₃ and H₄ Receptors

The modulation of biological processes with light-sensitive chemical probes promises precise temporal and spatial control. Yet, the design and synthesis of suitable probes is a challenge for medicinal chemists. This article introduces a photocaging strategy designed to modulate the pharmacology of h...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Yang Zheng, Meichun Gao, Maikel Wijtmans, Henry F. Vischer, Rob Leurs
Format:	Article
Language:	English
Published:	MDPI AG 2024-04-01
Subjects:	photocaging BODIPY cage histamine H<sub>3</sub> receptor H<sub>4</sub> receptor
Online Access:	https://www.mdpi.com/1424-8247/17/4/536