Levodopa responsive freezing of gait is associated with reduced norepinephrine transporter binding in Parkinson's disease

Background: Freezing of gait (FOG) is a major cause of falling in Parkinson's disease (PD) and can be responsive or unresponsive to levodopa. Pathophysiology is poorly understood. Objective: To examine the link between noradrenergic systems, the development of FOG in PD and its responsiveness t...

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發表在:	Neurobiology of Disease
Main Authors:	J. Lucas McKay, Jonathan Nye, Felicia C. Goldstein, Barbara Sommerfeld, Yoland Smith, David Weinshenker, Stewart A. Factor
格式:	Article
語言:	英语
出版:	Elsevier 2023-04-01
主題:	Parkinson's disease Freezing of gait Norepinephrine transporter Positron emission tomography Norepinephrine Primary progressive freezing of gait
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S0969996123000621