Impact of oral azithromycin and intermittent preventive treatment with sulfadoxine-pyrimethamine regimen on child mortality in Sierra Leone: trial protocol for a randomised, two-arm, double-blinded, placebo-controlled clinical trial (ICARIA)

Abstract Background Azithromycin has been shown to be beneficial in preventing infectious diseases, including malaria, infectious diarrhoea and pneumonia. A cluster randomised control trial on azithromycin MDA in children in Niger, Malawi and Tanzania found a reduction in all-cause under-five (U5) m...

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Bibliographic Details

Published in:	Trials
Main Authors:	Kwabena Owusu-kyei, Haily Chen, Maureen Chileshe, Llorenç Quintó, Maya Sibley, Antía Figueroa-Romero, Mireia Llach, Máximo Ramírez, Andreu Bofill, Mohamed Samai, Clara Menéndez, ICARIA Trial Team
Format:	Article
Language:	English
Published:	BMC 2024-09-01
Subjects:	Azithromycin Placebo Intermittent preventive treatment Randomised controlled trial Mortality Macrolide resistance
Online Access:	https://doi.org/10.1186/s13063-024-08443-9