Curcuminoid Chalcones: Synthesis, Stability, and New Neuroprotective and Sonosensitising Activities

The primary purpose of this work was to design and obtain a series of curcuminoid chalcone–NSAID hybrid derivatives. The ester-type hybrid compounds with ibuprofen (<b>i</b>), ketoprofen (<b>ii</b>), and naproxen (<b>iii</b>) were obtained in two ways, using the C...

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Bibliographic Details
Published in:Pharmaceuticals
Main Authors: Dorota Olender, Małgorzata Józkowiak, Hanna Piotrowska-Kempisty, Katarzyna Sowa-Kasprzak, Lucjusz Zaprutko, Izabela Muszalska-Kolos, Ewa Baranowska-Wójcik, Dominik Szwajgier
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Subjects:
curcuminoid chalcones
hybrids
NSAIDs
Claisen–Schmidt reaction
Steglich esterification reaction
sonodynamic therapy
Online Access:https://www.mdpi.com/1424-8247/16/9/1331

Internet

https://www.mdpi.com/1424-8247/16/9/1331

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