Augmented drug combination dataset to improve the performance of machine learning models predicting synergistic anticancer effects

Abstract Combination therapy has gained popularity in cancer treatment as it enhances the treatment efficacy and overcomes drug resistance. Although machine learning (ML) techniques have become an indispensable tool for discovering new drug combinations, the data on drug combination therapy currentl...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Mengmeng Liu, Gopal Srivastava, J. Ramanujam, Michal Brylinski
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-01-01
Online Access:	https://doi.org/10.1038/s41598-024-51940-9