Characterization of two novel VIM-type metallo-β-lactamases, VIM-84 and VIM-85, associated with the spread of IncP-2 megaplasmids in Pseudomonas aeruginosa

ABSTRACT This study aimed to characterize two novel VIM-type metallo-β-lactamases, VIM-84 and VIM-85, and reveal the important role of the IncP-2 type megaplasmids in the spread of antimicrobial resistance (AMR) genes. VIM-84 and VIM-85 were encoded by two novel genes bla VIM-84 and bla VIM-85 which...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Nanfei Wang, Tailong Lei, Yiwei Zhu, Yue Li, Heng Cai, Piaopiao Zhang, Sebastian Leptihn, Junxin Zhou, Huanhuan Ke, Bo Gao, Yu Feng, Xiaoting Hua, Tingting Qu
Format:	Article
Language:	English
Published:	American Society for Microbiology 2023-10-01
Subjects:	Pseudomonas aeruginosa metallo-β-lactamase VIM megaplasmid antimicrobial resistance
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.01544-23