Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVID.

<h4>Background</h4>Despite considerable effort, the genetic factors responsible for >90% of the antibody deficiency syndromes IgAD and CVID remain elusive. To produce a functionally diverse antibody repertoire B lymphocytes undergo class switch recombination. This process is initiated...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Steven M Offer, Qiang Pan-Hammarström, Lennart Hammarström, Reuben S Harris
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-08-01
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20805886/pdf/?tool=EBI