Dopamine D2-Subtype Receptors Outside the Blood-Brain Barrier Mediate Enhancement of Mesolimbic Dopamine Release and Conditioned Place Preference by Intravenous Dopamine

Dopamine (DA) is a cell-signaling molecule that does not readily cross the blood-brain barrier. Despite this, peripherally administered DA enhances DA levels in the nucleus accumbens and alters DA-related behaviors. This study was designed to investigate whether DA subtype-2 receptors are involved i...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	J. Daniel Obray, Christina A. Small, Emily K. Baldwin, Eun Young Jang, Jin Gyeom Lee, Chae Ha Yang, Jordan T. Yorgason, Scott C. Steffensen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Subjects:	dopamine microdialysis dopamine 2 receptor domperidone ventral tegmental area nucleus accumbens
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2022.944243/full