Flavylium-Based Hypoxia-Responsive Probe for Cancer Cell Imaging

A hypoxia-responsive probe based on a flavylium dye containing an azo group (<b>AZO-Flav</b>) was synthesized to detect hypoxic conditions via a reductase-catalyzed reaction in cancer cells. In in vitro enzymatic investigation, the azo group of <b>AZO-Flav</b> was reduced by...

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Bibliographic Details
Published in:Molecules
Main Authors: Thitima Pewklang, Sirawit Wet-osot, Sirilak Wangngae, Utumporn Ngivprom, Kantapat Chansaenpak, Chuthamat Duangkamol, Rung-Yi Lai, Parinya Noisa, Mongkol Sukwattanasinitt, Anyanee Kamkaew
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Subjects:
flavylium
azo dye
hypoxia detection
turn-on fluorescent sensor
activity-based sensing
Online Access:https://www.mdpi.com/1420-3049/26/16/4938

Internet

https://www.mdpi.com/1420-3049/26/16/4938

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