Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice

Passive immunotherapy is a very promising approach for the treatment of Alzheimer’s disease (AD). Among the different antibodies under development, those targeting post-translationally modified Aβ peptides might combine efficient reduction in beta-amyloid accompanied by lower sequestration in periph...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Kathrin Gnoth, Stefanie Geissler, Julia Feldhaus, Nadine Taudte, Victoria Ilse, Sebastian Zürner, Sebastian Greiser, Ulf-Dietrich Braumann, Jens-Ulrich Rahfeld, Holger Cynis, Stephan Schilling
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Subjects:	passive immunotherapy CD33 knock out amyloid beta 5xFAD mouse model Alzheimer’s disease
Online Access:	https://www.mdpi.com/2218-273X/12/3/399