Improving Chromatin-Interaction Prediction Using Single-Cell Open-Chromatin Profiles and Making Insight Into the Cis-Regulatory Landscape of the Human Brain

Single-cell open-chromatin profiles have the potential to reveal the pattern of chromatin-interaction in a cell type. However, currently available cis-regulatory network prediction methods using single-cell open-chromatin profiles focus more on local chromatin interactions despite the fact that long...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Neetesh Pandey, Omkar Chandra, Shreya Mishra, Vibhor Kumar
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-10-01
Subjects:	chromatin-interaction single-cell epigenome single-cell ATAC-seq GWAS target long-range brain cis-interaction
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2021.738194/full