The role of doxorubicin in the formation of cardiotoxicity is a consensus statement. Part II. Cardiotoxicity of doxorubicin unrelated to myocytes and cardioprotection strategy (review)

Introduction. The use of doxorubicin in clinical practice has shown cumulative and dose-dependent toxic effects on cardiomyocytes, leading to an increase of mortality risk among patients with cancer and as a resulting to restrictions in the indications for its use.Text. A dangerous adverse reaction...

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Bibliographic Details

Published in:	Разработка и регистрация лекарственных средств
Main Authors:	D. A. Andreev, E. I. Balakin, A. S. Samoilov, V. I. Pustovoit
Format:	Article
Language:	Russian
Published:	LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2024-09-01
Subjects:	anthracycline chemotherapy drug doxorubicin cardiotoxicity cardiomyocytes mitochondria
Online Access:	https://www.pharmjournal.ru/jour/article/view/1913