p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition

Ageing normal oesophagus epithelium contains p53 mutant clones. Here the authors use transgenic mice to show how these clones form and contribute to cancer development.

書誌詳細
出版年:Nature Communications
主要な著者: Kasumi Murai, Stefan Dentro, Swee Hoe Ong, Roshan Sood, David Fernandez-Antoran, Albert Herms, Vasiliki Kostiou, Irina Abnizova, Benjamin A. Hall, Moritz Gerstung, Philip H. Jones
フォーマット: 論文
言語:英語
出版事項: Nature Portfolio 2022-10-01
オンライン･アクセス:https://doi.org/10.1038/s41467-022-33945-y

インターネット

https://doi.org/10.1038/s41467-022-33945-y

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