Regulatory mechanisms of PD-1/PD-L1 in cancers

Abstract Immune evasion contributes to cancer growth and progression. Cancer cells have the ability to activate different immune checkpoint pathways that harbor immunosuppressive functions. The programmed death protein 1 (PD-1) and programmed cell death ligands (PD-Ls) are considered to be the major...

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Bibliographic Details
Published in:Molecular Cancer
Main Authors: Xin Lin, Kuan Kang, Pan Chen, Zhaoyang Zeng, Guiyuan Li, Wei Xiong, Mei Yi, Bo Xiang
Format: Article
Language:English
Published: BMC 2024-05-01
Subjects:
Tumor immunity
PD-1
PD-L1
Regulatory mechanism
Combination therapy
Online Access:https://doi.org/10.1186/s12943-024-02023-w

Internet

https://doi.org/10.1186/s12943-024-02023-w

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