A Distance-Based Kernel Association Test Based on the Generalized Linear Mixed Model for Correlated Microbiome Studies

Researchers have increasingly employed family-based or longitudinal study designs to survey the roles of the human microbiota on diverse host traits of interest (e. g., health/disease status, medical intervention, behavioral/environmental factor). Such study designs are useful to properly control fo...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Hyunwook Koh, Yutong Li, Xiang Zhan, Jun Chen, Ni Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-05-01
Subjects:	microbiome association studies correlated microbiome studies longitudinal microbiome studies community-level association analysis distance-based association analysis adaptive association analysis
Online Access:	https://www.frontiersin.org/article/10.3389/fgene.2019.00458/full