The Phenoxyphenol Compound diTFPP Mediates Exogenous C₂-Ceramide Metabolism, Inducing Cell Apoptosis Accompanied by ROS Formation and Autophagy in Hepatocellular Carcinoma Cells

Hepatocellular carcinoma (HCC) is a severe disease that accounts for 80% of liver cancers. Chemotherapy is the primary therapeutic strategy for patients who cannot be treated with surgery or who have late-stage HCC. C₂-ceramide is an effective reagent that has been found to in...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Wen-Tsan Chang, Yung-Ding Bow, Yen-Chun Chen, Chia-Yang Li, Jeff Yi-Fu Chen, Yi-Ching Chu, Yen-Ni Teng, Ruei-Nian Li, Chien-Chih Chiu
Format:	Article
Language:	English
Published:	MDPI AG 2021-03-01
Subjects:	hepatocellular carcinoma (HCC) phenoxyphenol compound diTFPP ROS apoptosis autophagy
Online Access:	https://www.mdpi.com/2076-3921/10/3/394