Development and characterization of an intra‐articular fracture mediated model of post‐traumatic osteoarthritis

Abstract Purpose This study aimed to develop and characterize a closed intra‐articular fracture (IAF) mediated post‐traumatic osteoarthritis (PTOA) model in rats to serve as a testbed for putative disease modifying interventions. Methods Male rats were subject to a 0 Joule (J), 1 J, 3 J, or 5 J blun...

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Bibliographic Details

Published in:	Journal of Experimental Orthopaedics
Main Authors:	Michael S. Valerio, William A. Pace, Connor P. Dolan, Jorge B. Edwards, Naveena B. Janakiram, Benjamin K. Potter, Christopher L. Dearth, Stephen M. Goldman
Format:	Article
Language:	English
Published:	Wiley 2023-01-01
Subjects:	Animal Models Musculoskeletal System Trauma Comminuted Fractures Military Personnel Regenerative Medicine
Online Access:	https://doi.org/10.1186/s40634-023-00625-9