Synthesis, In Vitro α-Glucosidase Inhibitory Activity and Molecular Docking Study of New Benzotriazole-Based Bis-Schiff Base Derivatives

This study was carried out to synthesize benzotriazole-based bis-Schiff base scaffolds (<b>1</b>–<b>20</b>) and assess them in vitro for <i>α</i>-glucosidase inhibitory potentials. All the synthetics analogs based on benzotriazole-based bis-Schiff base scaffolds w...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Imran Khan, Wajid Rehman, Fazal Rahim, Rafaqat Hussain, Shoaib Khan, Srosh Fazil, Liaqat Rasheed, Muhammad Taha, Syed Adnan Ali Shah, Magda H. Abdellattif, Thoraya A. Farghaly
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Subjects:	synthesis α-glucosidase benzotriazole bis-Schiff base structure activity relationship molecular docking
Online Access:	https://www.mdpi.com/1424-8247/16/1/17