Association Between Progranulin and Gaucher Disease

Background: Gaucher disease (GD) is a genetic disease caused by mutations in the GBA1 gene which result in reduced enzymatic activity of β-glucocerebrosidase (GCase). This study identified the progranulin (PGRN) gene (GRN) as another gene associated with GD. Methods: Serum levels of PGRN were measur...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:EBioMedicine
المؤلفون الرئيسيون: Jinlong Jian, Shuai Zhao, Qing-Yun Tian, Helen Liu, Yunpeng Zhao, Wen-Chi Chen, Gabriele Grunig, Paola A. Torres, Betty C. Wang, Bai Zeng, Gregory Pastores, Wei Tang, Ying Sun, Gregory A. Grabowski, Max Xiangtian Kong, Guilin Wang, Ying Chen, Fengxia Liang, Herman S. Overkleeft, Rachel Saunders-Pullman, Gerald L. Chan, Chuan-ju Liu
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Elsevier 2016-09-01
الموضوعات:
Progranulin
β-Glucocerebrosidase
Gaucher disease
Lysosomal storage diseases
الوصول للمادة أونلاين:http://www.sciencedirect.com/science/article/pii/S235239641630353X

الانترنت

http://www.sciencedirect.com/science/article/pii/S235239641630353X

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