Regulation mechanism of endoplasmic reticulum stress on metabolic enzymes in liver diseases
The endoplasmic reticulum (ER) plays a pivotal role in protein folding and secretion, Ca2+ storage, and lipid synthesis in eukaryotic cells. When the burden of protein synthesis and folding required to be handled exceeds the processing capacity of the ER, the accumulation of misfolded/unfolded prote...
| Published in: | Pharmacological Research |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-09-01
|
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1043661824002779 |