Impact of tissue factor expression and administration routes on thrombosis development induced by mesenchymal stem/stromal cell infusions: re-evaluating the dogma

Abstract Background Hyperactive coagulation might cause dangerous complications such as portal vein thrombosis and pulmonary embolism after mesenchymal stem/stromal cell (MSC) therapy. Tissue factor (TF), an initiator of the extrinsic coagulation pathway, has been suggested as a predictor of this pr...

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Bibliographic Details

Published in:	Stem Cell Research & Therapy
Main Authors:	Van T. Hoang, Duc Son Le, Duc M. Hoang, Trang Thi Kieu Phan, Lan Anh Thi Ngo, Trung Kien Nguyen, Viet Anh Bui, Liem Nguyen Thanh
Format:	Article
Language:	English
Published:	BMC 2024-02-01
Subjects:	Cell therapy Coagulation Mesenchymal stem cell Mesenchymal stromal cell Tissue factor Thrombosis
Online Access:	https://doi.org/10.1186/s13287-023-03582-3