Mechanistic and therapeutic insights into the function of NLRP3 inflammasome in sterile arthritis

The NLRP3 inflammasome, which belongs to the pyrin domain containing 3 family of NOD-like receptors, has a significant impact on both the innate and adaptive immune responses. Regulating host immune function and protecting against microbial invasion and cell damage, the NLRP3 inflammasome plays a cr...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Yi Xiao, Li Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Subjects:	NLRP3 inflammasome pyroptosis inflammation arthritis immune system
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1273174/full