Preparation and Optimization of 10-Hydroxycamptothecin Nanocolloidal Particles Using Antisolvent Method Combined with High Pressure Homogenization

The aim of this study was to prepare 10-hydroxycamptothecin nanocolloidal particles (HCPTNPs) to increase the solubility of drugs, reduce the toxicity, improve the stability of the drug, and so forth. HCPTNPs was prepared by antisolvent precipitation (AP) method combined with high pressure homogeniz...

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Bibliographic Details
Published in:Journal of Chemistry
Main Authors: Bolin Lian, Yong Li, Xiuhua Zhao, Yuangang Zu, Ying Wang, Yin Zhang, Yuanyuan Li
Format: Article
Language:English
Published: Wiley 2017-01-01
Online Access:http://dx.doi.org/10.1155/2017/5752090