Ribonuclease H1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasion.
Switching of the Variant Surface Glycoprotein (VSG) in Trypanosoma brucei provides a crucial host immune evasion strategy that is catalysed both by transcription and recombination reactions, each operating within specialised telomeric VSG expression sites (ES). VSG switching is likely triggered by e...
| الحاوية / القاعدة: | PLoS Genetics |
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| المؤلفون الرئيسيون: | , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Public Library of Science (PLoS)
2018-12-01
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| الوصول للمادة أونلاين: | https://doi.org/10.1371/journal.pgen.1007729 |