Large-Scale Transcriptome Profiling and Network Pharmacology Analysis Reveal the Multi-Target Inhibitory Mechanism of Modified Guizhi Fuling Decoction in Prostate Cancer Cells

<b>Background:</b> Prostate cancer (PCa) is the primary contributor to male cancer-related mortality and currently lacks effective treatment options. The Modified Guizhi Fuling Decoction (MGFD) is used in clinical practice to treat multiple tumors. This research focused on the mechanisms...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Guochen Zhang, Lei Xiang, Qingzhou Li, Mingming Wei, Xiankuo Yu, Yan Luo, Jianping Chen, Xilinqiqige Bao, Dong Wang, Shiyi Zhou
Format:	Article
Language:	English
Published:	MDPI AG 2025-08-01
Subjects:	prostate cancer Modified Guizhi Fuling Decoction HTS<sup>2</sup> technology network pharmacology transcriptomics bioinformatics
Online Access:	https://www.mdpi.com/1424-8247/18/9/1275