miR-155 Regulates IL-10-Producing CD24hiCD27+ B Cells and Impairs Their Function in Patients with Crohn’s Disease

Regulatory interleukin-10 (IL-10)-producing B cells (B10 cells) play a critical role in preventing and curing autoimmune diseases in experimental mouse models. However, the precise cellular and molecular mechanisms of action of B10 cells in humans, especially in patients with Crohn’s disease (CD), r...

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发表在:	Frontiers in Immunology
Main Authors:	Yingxia Zheng, Wensong Ge, Yanhui Ma, Guohua Xie, Weiwei Wang, Li Han, Bingxian Bian, Li Li, Lisong Shen
格式:	文件
语言:	英语
出版:	Frontiers Media S.A. 2017-08-01
主题:	miR-155 CD24hiCD27+ B cells B10 cells Crohn’s disease IL-10
在线阅读:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00914/full