A systematic framework for predictive biomarkers in immune effector cell-associated neurotoxicity syndrome

Chimeric antigen receptor (CAR)-T cell therapy has revolutionized the management of several life-threatening malignancies, often achieving durable sustained responses. The number of patients treated with this new class of cell-based therapy, along with the number of Food and Drug Association (FDA) a...

Full description

Bibliographic Details

Published in:	Frontiers in Neurology
Main Authors:	Omar H. Butt, Alice Y. Zhou, Beau M. Ances, John F. DiPersio, Armin Ghobadi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-02-01
Subjects:	ICANS neurotoxicity predictive biomarker review cellular therapies CRS
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2023.1110647/full