V(D)J Recombination Excision Circles of B- and T-cells as Prognostic Marker in B-Cell Chronic Lymphocytic Leukemia

Background & Aims. T-cell receptor excision circles (TREC) and κ-deleting recombination excision circles (KREC) are extrachromosomal DNA segments generated during V(D)J re combination process that characterize the diversity of the antigen repertoire of T- and B-cells. The aim of our study is to...

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Bibliographic Details

Published in:	Клиническая онкогематология
Main Authors:	IV Obraztsov, MA Gordukova, NA Severina, BV Biderman, SYu Smirnova, AB Sudarikov, EA Nikitin, AG Rumyantsev
Format:	Article
Language:	Russian
Published:	Practical Medicine Publishing House 2017-04-01
Subjects:	CLL TREC KREC naive T-cells naive B-cells biomarkers outcome predictors
Online Access:	http://bloodjournal.ru/wp-content/uploads/2017/03/1.pdf