ISG15/USP18/STAT2 is a molecular hub regulating IFN I-mediated control of Dengue and Zika virus replication

The establishment of a virus infection is the result of the pathogen's ability to replicate in a hostile environment generated by the host's immune system. Here, we found that ISG15 restricts Dengue and Zika viruses' replication through the stabilization of its binding partner USP18....

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發表在:	Frontiers in Immunology
Main Authors:	Constanza Eleonora Espada, Edroaldo Lummertz da Rocha, Taissa Ricciardi-Jorge, Adara Aurea dos Santos, Zamira Guerra Soares, Greicy Malaquias, Daniel Oliveira Patrício, Edgar Gonzalez Kozlova, Paula Fernandes dos Santos, Juliano Bordignon, Thomas J. Sanford, Teodoro Fajardo, Trevor R. Sweeney, André Báfica, Daniel Santos Mansur
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2024-02-01
主題:	Dengue virus Zika virus ISG15 USP18 type one interferon ISGylation
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1331731/full