Timing of Transcriptomic Peripheral Blood Mononuclear Cell Responses of Sheep to Fasciola hepatica Infection Differs From Those of Cattle, Reflecting Different Disease Phenotypes

Infection with the zoonotic trematode Fasciola hepatica, common in many regions with a temperate climate, leads to delayed growth and loss of productivity in cattle, while infection in sheep can have more severe effects, potentially leading to death. Previous transcriptomic analyses revealed upregul...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Dagmara A. Niedziela, Amalia Naranjo-Lucena, Verónica Molina-Hernández, John A. Browne, Álvaro Martínez-Moreno, José Pérez, David E. MacHugh, Grace Mulcahy
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-09-01
Subjects:	transcriptomics sheep PBMC Fasciola anti-inflammatory response
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.729217/full